Publications

Recent Publications

E. Boltcreed, A. Ersöz, M. Han, and G. McConnell (2023), “Effects of Gamma Stimulation on Neuroinflammation at the Tissue-Electrode Interface in Motor Cortex,” Neuromodulation: Technology at the Neural Interface. DOI: https://doi.org/10.1016/j.neurom.2023.11.003

Ersöz, A., I. Kim, and M. Han (2023) “Charge Injection Enhancement Comparisons of Iridium Oxide Microelectrodes In Vitro and In Vivo” 2023 11th International IEEE/EMBS Conference on Neural Engineering (NER), IEEE Engineering in Medicine and Biology Society. DOI: 10.1109/NER52421.2023.10123832.

Ersöz, A., I. Kim, and M. Han (2022) “A portable neurostimulator circuit with anodic bias enhances stimulation injection capacity” Journal of Neural Engineering DOI: https://doi.org/10.1088/1741-2552/ac8fb6

McCreery D.B., M. Han, V. Pikov, C. Miller (2021) “Configuring intracortical microelectrode arrays and stimulus parameters to minimize neuronloss during prolonged intracortical electrical stimulation” Brain Stimulation. DOI: https://doi.org/10.1016/j.brs.2021.10.385

Santaniello, Sabato, George C. McConnell, John T. Gale, Rose Taj Faghih, Caleb Kemere, Justin David Hilliard, and Martin Han (eds.) (2021) “Editorial: Towards the Next Generation of Deep Brain Stimulation Therapies: Technological Advancements, Computational Methods, and New Targets” vol. 1, Frontiers in Neuroscience–Neuroprosthetics. DOI: http://doi.org/10.3389/fnins.2021.737737

Santaniello, Sabato, George C. McConnell, John T. Gale, Rose Taj Faghih, Caleb Kemere, Justin David Hilliard, and Martin Han (eds.) (2021) “Towards the Next Generation of Deep Brain Stimulation Therapies: Technological Advancements, Computational Methods, and New Targets” vol. 1, Frontiers in Neuroscience–Neuroprosthetics. e-Book PDF:

Han, M. and D. B. McCreery (2021) “Future Development: Penetrating Multisite Microelectrodes as Cochlear Nucleus Implant,” in “AuditoryBrainstem Implants.” E. P. Wilkinson and M. S. Schwartz. Thieme Medical Publishers. NLM ID#101772397. eISBN 978-1-62623-827-5.

T Guo, SP Patel, D Shah, L Chi, S Emadi, DM Pierce, M Han, P Rodolfo Brumovsky, B Feng (2021) “Optical clearing reveals TNBS-induced morphological changes of VGLUT2-positive nerve endings in mouse colorectum.” American Journal of Physiology-Gastrointestinal and Liver Physiology. DOI: 10.1152/ajpgi.00363.2020

Ersoz, A., I. Kim and M. Han (2021). “Maximizing Charge Injection Limits of Iridium Oxide Electrodes with a Programmable Anodic Bias Circuit” 2021 10th International IEEE/EMBS Conference on Neural Engineering (NER), IEEE Engineering in Medicine and Biology Society. DOI: https://doi.org/10.1109/NER49283.2021.9441282

McNamara, M., A. Ersoz and M. Han (2021). “A Diagnostic Circuit for Crosstalk Detection in Microelectrode Arrays” 2021 10th International IEEE/EMBS Conference on Neural Engineering (NER), IEEE Engineering in Medicine and Biology Society. DOI: https://doi.org/10.1109/NER49283.2021.9441164

Niemiec, M. and M. Han (2021). “A Simple Table-Top Technique for Multi-Signal Pseudo-Extracellular Recording” 2021 10th International IEEE/EMBS Conference on Neural Engineering (NER), IEEE Engineering in Medicine and Biology Society. DOI: https://doi.org/10.1109/NER49283.2021.9441208

Nolta, N. F., P Ghelich, A. Ersoz, and M Han (2020), “Fabrication and Modeling of Recessed Traces for Silicon-Based Neural Microelectrodes”  Journal of Neural Engineering https://doi.org/10.1088/1741-2552/abb9bd

Pikov, V., D. B. McCreery and M. Han (2020), “Intraspinal Stimulation with Silicon-Based 3D Microelectrode Array for Bladder Voiding in Cats” Journal of Neural Engineering DOI: https://doi.org/10.1088/1741-2552/abca13

Ghelich, P., Nolta, N., and Han M. (2021), “Unprotected Sidewalls in  Implantable Silicon Devices and Conformal Coating as a Solution” npj Materials Degradation. DOI: 10.1038/s41529-021-00154-9

Nolta, N. F., A. Liberti, R. Makol, and M. Han (2020) “Gelatin Embedding and LED Autofluorescence Reduction for Rodent Spinal Cord Histology” Journal of Neuroscience Methods, DOI: 10.1016/j.jneumeth.2020.108924

Guo T, Chen L, Tran K, Ghelich P, Guo YS, Nolta N, Han M, Feng B. (2020) “Extracellular single-unit recordings from mouse peripheral nerve axons by a novel multichannel microelectrode array in vitro” Sensors and Actuators B: Chemical. doi.org/10.1016/j.snb.2020.128111

Nolta, N. F., P. Ghelich, and M. Han (2020), “Fabrication and Modeling of Recessed Traces for Silicon-Based Neural Microelectrodes,” bioRxiv, doi.org/10.1101/2020.04.06.028159

Ersoz, Alpaslan, Helen Phu, Insoo Kim, and Martin Han (2019). “A Wireless Neurostimulator System with an Embedded ARM™ Microprocessor.” IEEE EMBC, Berlin, Germany, July 23-27, 2019. Prog. No. 2636. DOI:10.1109/EMBC.2019.8856311

Nolta, Nicholas F., Pejman Ghelich, and Martin Han (2019). “Recessed Traces for Planarized Passivation of Chronic Neural Microelectrodes.” IEEE EMBC, Berlin, Germany, July 23-27, 2019. Program. No. 2504. DOI:10.1109/EMBC.2019.8857171

Nambiar, A., Nolta, N., and Han, M. (2019). “3D Reconstruction of the Intracortical Volume Around a Hybrid Microelectrode Array.”  Frontiers in Neuroscience 13 (393). doi: 10.3389/fnins.2019.00393. PMID: 31068786

McCreery, D. B., Yadav, K., Han, M. (2018). “Responses of neurons in the feline inferior colliculus to modulated electrical stimuli applied on andwithin the ventral cochlear nucleus; Implications for an advanced auditory brainstem implant.” Hearing Research (363): 85-97.10.1016/j.heares.2018.03.009

 

Other Publications

Frontiers listing

 

Recent Conference Presentations

M. J. Schneider, A. F. Karimi, D. B. McCreery, and M. Han (2023), “Assessing reliability of multisite silicon chronic arrays through accelerated soak testing and circuit modeling,” in Society for Neuroscience Annual Meeting, Washington, D.C., November 12, 2023, Program No. 117.23.

E. Boltcreed, A. Ersoz, M. Han, and G. Mcconnell (2023), “Effects of Gamma Stimulation on Neuroinflammation at the Tissue-Electrode Interface,” in Society for Neuroscience Annual Meeting, Washington, D.C., November 12, 2023, Program No. 2977.

Sands, I., A. Ersoz, W. Zhang, L. Zhou, W. Linthicum, S. Santaniello, B. Huey, M. Han and Y. Chen (2023). “DNA-Inspired Electrically Conductive Nanocoating for Intracortical Microelectrode Stimulation and Recording.” Society of Biomaterials, San Diego, CA, 2023.

Ersoz, A., Kim, I., and Han, M. (2022). “A Wireless and Portable 16-Channel Neurostimulator System with Voltage Transient Monitoring and Artificial Evoked Potential Recording” in Gordon Research Conference: Neuroelectronic Interfaces. 2022. Ventura, CA. Program No. Mon-Tue 27.

Keri, N., I. Sands, P. Ghelich, L. Zhou, W. Zhang, N. Nolta, W. Linthicum, B. Huey, Y. Chen and M. Han (2020). “Electrochemical Characterization of Nanotube Coating on Silicon-Based Microelectrodes.” Materials Research Society Virtual Spring/Fall Meeting, Virtual. Program No. F.FL02.07.02.

Sands, I., N. Keri, P. Ghelich, L. Zhou, W. Zhang, N. Nolta, M. Han and Y. Chen (2020). “Electrically Conductive Janus Base Nano-Coating For Brain Machine Interface Enhancement.” Biomedical Engineering Society Annual Meeting, Virtual. Prog. No. 735.

Ersöz, A., I. Kim and M. Han (2020). “A Portable and Multifunctional 16-Channel Neurostimulator System.” Connecticut Symposium on Microelectronics & Optoelectronics: 29th Annual Symposium-Virtual. Prog. No. P19.

Ghelich, P., N. Nolta, N. Keri and M. Han (2020). “Sputtered Iridium Oxide Film (SIROF) Characterization on Implantable Neural Microelectrodes.” Connecticut Symposium on Microelectronics & Optoelectronics: 29th Annual Symposium-Virtual. Prog. No. P16.

Keri, N., I. Sands, L. Zhou, Y. Chen and M. Han (2020). “Electrochemical characterization of nanotube coatings on silicon-based microelectrodes.” Connecticut Symposium on Microelectronics & Optoelectronics: 29th Annual Symposium-Virtual. Prog. No. P15.

Nolta, N., P. Ghelich and M. Han (2020). “Fabrication of Recessed Traces for Improved Longevity of Implantable MEMS.” Connecticut Symposium on Microelectronics & Optoelectronics: 29th Annual Symposium-Virtual. (Oral Presentation)

Riley, A., S. Santaniello and M. Han (2020). “Optimization of the Temporal Profile of DBS Therapy for Parkinson’s Disease.” 6th Annual IEEE MIT Undergraduate Research Technology Conference Virtual, Prog. No. PO20-0021.

Dixit, K., P. Ghelich, L. Zhao, E. S. Kim and M. Han (2020). “A Chronic Assembly for an Implantable Focused Ultrasound Stimulator in the Rat Spinal Cord.” in North American Neuromodulation Society Annual Conference, Las Vegas, NV. Program No. PS7.

Nolta, N., P. Ghelich and M. Han (2020). “Pre-Clinical Validation of Silicon-Based Auditory Brainstem Prostheses.” in Association for Research in Otolaryngology—43rd Annual MidWinter Meeting, San Jose, CA. Program No. PS582.

Nolta, N., P. Ghelich, and M. Han (2019). “Recessed traces for low-stress passivation of chronic penetrating silicon microelectrodes,” in Society for Neurscience Annual Meeting, Chicago, IL, Program No. 522.01.

Ersoz, H. Phu, I. Kim, and M. Han (2019). “A portable neurostimulator with wirelessly adjusted constant-current waveforms and bias voltage,” in Society for Neurscience Annual Meeting, Chicago, IL, Program No. 522.02.

Ghelich, N. F. Nolta, and M. Han (2019). “Comparison of sputtered iridium and sputtered iridium oxide on silicon-based neural microelectrodes,” in Society for Neurscience Annual Meeting, Chicago, IL, Program No. 522.03.

Ilham, S. J., N. F. Nolta, C. Hardy, P. Smith, and M. Han (2019). “Techniques for spinal cord stimulation to restore bladder function in rats.” Society for Neuroscience Annual Meeting, Chicago, IL, Program No. 747.05.

Patel, N. Ganeshbabu, T. Guo, M. Han, and B. Feng (2019). “Quantification of nerve endings in mouse colorectum by optical tissue clearing and automatic image processing,” in Society for Neurscience Annual Meeting, Chicago, IL, Program No. 251.10.

Guo, L. Chen, S. J. Ilham, N. F. Nolta, M. Han, and B. Feng (2019), “Selective DRG neuromodulation by flexible parylene based electrode array,” in Society for Neurscience Annual Meeting, Chicago, IL, 2019, Program No. 797.09.

Nambiar, Aparna, Nicholas Nolta, and M. Han (2018). “Development of Tools for a 3D Reconstructed Intracortical Volume Around Microelectrode Arrays.” In Society for Neuroscience, No. 769.02. San Diego, CA.

Nolta, Nicholas, Pejman Ghelich, Michael Jacobs, and M.Han (2018). “Fabrication, testing, and refinement of a silicon-based cochlear nucleus array.” In Society for Neuroscience, No. 700.21. San Diego, CA.

Han, Martin, and Douglas B. McCreery (2018). “Validation of Advanced Cochlear Nucleus Auditory Prosthesis With 3D Penetrating Microelectrode Arrays.” In Society for Neuroscience, No. 394.21. San Diego, CA.

Nolta, Nicholas, Pejman Ghelich, Michael Jacobs, and M.Han (2018). “Progress Towards a Silicon-Based Cochlear Nucleus Hearing Prosthesis.” In Materials Research Society Fall Meeting, No. BM07.09.07. Boston, MA.

Nambiar, A., N. Nolta, and M. Han (2018). “Development of Tools for a 3D Reconstructed Intracortical Volume Around Microelectrode Arrays.” in Neural Interfaces Conference. 2018. Minneapollis, MN. Program No. Mon-25.

Han, M. and D.B. McCreery (2018). “Enabling Study of Modulation Frequencies and Modulation Depths for Cochlear Nucleus Auditory Prosthesis.” in Neural Interfaces Conference. 2018. Minneapollis, MN. Program No. Tue-88.

Han, M., D. McCreery, N. Nolta, and A. Nambiar (2018). “A Hybrid Array and 3D Tissue Reconstruction for the Study of Intracortical Neural Interfaces.” in Gordon Research Conference: Neuroelectronic Interfaces. 2018. Galveston, TX. Program No. Wed/Thu 25.

Han, M. and D. McCreery (2017). “Encoding of Modulation Frequencies and Depths by Surface and Micro Electrodes for a Cochlear Nucleus Auditory Prosthesis.” in Society for Neuroscience Annual Meeting. Washington DC. Program No. 584.24.

Nolta, N., A. Nambiar, and M. Han (2017). “3D visualization of cellular biomarkers surrounding microwire/NeuroNexus/Blackrock “hybrid” arrays implanted chronically in cats.” in Society for Neuroscience, Washington DC. Program No. 594.18.

 

Undergraduate Conference Presentations

*Undergraduate Research Travel Awardees

*Weiyi Zhang and M. Han (2024), “Continuous Interleaved Sampling Based Sound Processing Strategy For An Auditory Brainstem Implant,” in IEEE MIT Undergraduate Research Technology Conference, Cambridge, MA, October 11-13, 2024.

R. L. Bender, M. Schneider, and M. Han (2023), “Increasing the Intensity of a UV Laser System to Etch Parylene C at the Micron Scale,” in IEEE MIT Undergraduate Research Technology Conference, Cambridge, MA, October 6-8, 2023. Virtual Poster Session #2 ID-261.

N. A. Azimov, M. Schneider, and M. Han (2023), “Dewarping and Alignment of Serial Confocal Sections for 3D Reconstruction of Neural Implant Volumes,” in IEEE MIT Undergraduate Research Technology Conference, Cambridge, MA, October 6-8, 2023. In-Person Poster Session #1 ID-238.

Bender, R. and M. Han (2023). “Increasing the Intensity of a UV Laser System to Etch Parylene C at the Micron Scale” in 2023 Frontiers Undergraduate Research Poster Exhibition, Storrs, CT. Prog. p. 41.

Kamath, N. and M. Han (2023). “Construction of a Microelectrode Array Using a Platinum Microwire Cable” in 2023 Frontiers Undergraduate Research Poster Exhibition, Storrs, CT. Prog. p. 43.

McNamara, M. and M. Han (2020). “A Diagnostic Electronic Circuit for Crosstalk Detection in Microelectrode Arrays” in 2020 Frontiers Undergraduate Research Online Exhibition, Storrs, CT. Prog. p. 57.

Woon, E. and M. Han (2020). “Focused Ultrasound Stimulation for Spinal Cord Injury” in 2020 Frontiers Undergraduate Research Online Exhibition, Storrs, CT. Prog. p. 94.

*Phu, A. Ersoz, and M. Han, “A User-Friendly Interface to Wirelessly Control Neuroprostheses,” in Biomedical Engineering Society Annual Meeting, Philadephia, PA, 2019, Prog. No. 4284.

*Mcnamara, A. Ersoz, and M. Han, “Crosstalk Detection Circuit for Microelectrode Arrays,” in Biomedical Engineering Society Annual Meeting, Philadephia, PA, 2019, Prog. No. 4282.

*Makol, N. F. Nolta, and M. Han, “Optimization of Immunohistochemical Staining Methods in Rat Spinal Cord Tissue,” in Biomedical Engineering Society Annual Meeting, Philadephia, PA, 2019, Prog. No. 4286.

*Liberti, A., N. Nolta, A. Nambiar, and M. Han (2018). “Characterization of Tissue Response In Rodent Spinal Cords by Immunofluorescence Staining.” in Biomedical Engineering Society Conference. Atlanta, GA. Prog. No. 3901.

*Johnson, A., A. Ersoz, and M. Han (2018). “Assembly of Compact Neurostimulator Circuit Board for Neuroprosthetic Applications. in Biomedical Engineering Society Conference.” Atlanta, GA. Prog. No. 3942.

Aslam, Y. and M. Han (2017). “Development of UV Laser System to Etch Parylene C at the Micron Scale.” in Biomedical Engineering Society Conference, Phoenix, AZ. Program No. 3367.

Makol, R. and M. Han (2019). “Optimization of Immunohistochemical Staining Methods in Rat Spinal Cord Tissue.” in 7th Annual Fall Frontiers Undergraduate Research Poster Exhibition Storrs, CT. Prog. No. 26.

McNamara, M. and M. Han (2019). Crosstalk Detection Circuit for Microelectrode Arrays.” in 7th Annual Fall Frontiers Undergraduate Research Poster Exhibition Storrs, CT. Prog. No. 50.

Phu, H. and M. Han (2019). A user-friendly interface to wirelessly control neuroprostheses.” in 7th Annual Fall Frontiers Undergraduate Research Poster Exhibition Storrs, CT. Prog. No. 49.

Johnson, A., A. Ersoz, and M. Han (2019). “Assembly of Compact Neurostimulator Circuit Board for Neuroprosthetic Applications.” in 22nd Annual Frontiers in Undergraduate Research. Storrs, UConn.

Johnson, Amanda, Alpaslan Ersoz, and Martin Han (2018). “Assembly of compact printed circuit board for neural stimulation and recording in neuroprosthetic applications.” In 22nd Annual Neuroscience at Storrs, Prog. No. 26.